Keri A Tallman Selected Research

Smith-Lemli-Opitz Syndrome

1/2021	Prescription Medications Alter Neuronal and Glial Cholesterol Synthesis.
1/2021	Generation and validation of a conditional knockout mouse model for the study of the Smith-Lemli-Opitz syndrome.
11/2020	Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis.
1/2019	Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment.
11/2017	Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone exposure.
10/2017	Propagation rate constants for the peroxidation of sterols on the biosynthetic pathway to cholesterol.
1/2017	Probes for protein adduction in cholesterol biosynthesis disorders: Alkynyl lanosterol as a viable sterol precursor.
2/2016	The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
1/2016	Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells.
10/2013	Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome.

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Keri A Tallman Research Topics

Disease

11	Smith-Lemli-Opitz Syndrome 01/2021 - 09/2011
2	Neurodevelopmental Disorders 01/2021 - 10/2013
2	Neuroblastoma 01/2020 - 01/2016
2	Atherosclerosis 12/2019 - 10/2014
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2020
1	Inflammation (Inflammations) 12/2019
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 12/2019
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2018
1	Dehydration (Water Stress) 10/2014
1	Parkinson Disease (Parkinson's Disease) 10/2014
1	Alzheimer Disease (Alzheimer's Disease) 10/2014
1	Asthma (Bronchial Asthma) 10/2014
1	Leukemia 03/2011
1	Colorectal Neoplasms (Colorectal Cancer) 03/2011
1	Colonic Neoplasms (Colon Cancer) 02/2008
1	Cardiovascular Diseases (Cardiovascular Disease) 02/2007

Drug/Important Bio-Agent (IBA)

7	CholesterolIBA 01/2020 - 09/2011
6	7-dehydrocholesterolIBA 01/2021 - 09/2011
5	Proteins (Proteins, Gene)FDA Link 12/2019 - 10/2013
3	OxysterolsIBA 11/2020 - 10/2014
2	SterolsIBA 01/2020 - 10/2017
2	7-dehydrocholesterol reductaseIBA 01/2019 - 11/2017
2	AldehydesIBA 10/2018 - 02/2007
1	Antidepressive Agents (Antidepressants)IBA 01/2021
1	EnzymesIBA 01/2021
1	Oxidoreductases (Dehydrogenase)IBA 01/2021
1	Trazodone (Trittico)FDA LinkGeneric 01/2021
1	Pharmaceutical PreparationsIBA 01/2020
1	Lysine (L-Lysine)FDA Link 12/2019
1	4-oxo-2-nonenalIBA 12/2019
1	HDL LipoproteinsIBA 12/2019
1	5,6-secosterolIBA 10/2018
1	trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane DihydrochlorideIBA 01/2016
1	OzoneIBA 10/2014
1	Peptides (Polypeptides)IBA 10/2014
1	Amino Acids FDA Link 10/2014
1	LipidsIBA 10/2013
1	7-ketocholesterolIBA 09/2011
1	Acetylcysteine (Siran)FDA LinkGeneric 03/2011
1	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 02/2008
1	Phospholipids (Phosphatides)FDA LinkGeneric 02/2007

Therapy/Procedure

1	Off-Label Use 01/2021